Normal salivary glands are made up of many different kinds of cells, and tumors can start in any of these cell types. The majority of these neoplasms are benign 80% and only 20% are malignant. Malignant sgts represent 6% of head and neck cancers and 0. Acinic cell carcinoma 3% of all salivary gland neoplasm 8090% in parotid 15% of all parotid tumors mean age is 4050 years 23 occur in female 3% shows bilateral involvement second most common salivary gland tumor in children well circumscribed tumor. Salivary glands make saliva, which aids in digestion, keeps your mouth moist and supports healthy teeth.
For malignant tumors, treatment is with excision and radiation. Salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. Mortality from malignant salivary gland neoplasms varies by stage and pathology, but the overall 5year survival rate is 72%. Salivary gland tumors are abnormal cells growing in the gland or in the tubes ducts that drain the salivary glands. The high grade carcinoma exhibits marked nuclear atypia with prominent nucleoli, frequent mitoses, and comedotype geographic tumor necrosis n. Dec, 2018 salivary cancers form in tissues of salivary glands in the floor of the mouth and throughout the oropharynx, the parotid glands, and the submandibular glands. Salivary gland tumors definition of salivary gland tumors.
You have three pairs of major salivary glands under and behind your jaw parotid, sublingual and submandibular. The cystic lesion has a mildly fibrotic appearing wall, is lined by histiocytes intermixed with rare lymphocytes, and contains mucous and macrophages. Neoplams of salivary glands tumors of salivary glands uncommon 3% to 6% of all tumors of head. Sep 28, 2017 although we know a few things that can raise a persons risk of salivary gland cancer, its not clear exactly what causes most of these cancers. Portion of a parotid gland demonstrating multiple foci of sebaceous differentiation. Salivary gland tumors are one of the most complex and relatively rare group of lesions encountered in oral pathology practice. Salivary gland tumors are rare types of tumors that begin in the salivary glands. Sep 28, 2017 salivary gland cancers malignant salivary gland tumors there are many types of salivary gland cancers. Salivary gland cancer is a type of head and neck cancer. Minor salivary glands netherland cancer institute, 2000 retrospective. Risk of salivary gland cancer after childhood cancer. Salivary gland neoplasms make up 6% of all head and neck tumors.
Definition a salivary gland tumor is an uncontrolled growth of cells that originates in one of the many salivaproducing glands in the mouth. Salivary gland tumors are benign, or noncancerous growths that are often removed without further need. Salivary gland cancers are named according to which of these cell types they most look like when seen under a microscope. Activity of chemotherapy in the palliative treatment of salivary gland tumors. Introduction salivary glands major parotid submandibular sublingual minor. The american joint committee for cancer staging and end result reporting ajcc has published a tumor, node, and metastases tnmbased staging system for major salivary gland malignancies. Larger the size of salivary gland, more the chance of tumor being benign. Characterization ie, benign or malignant, and histological type, location deep or superficial. Investigations such as fine needle aspiration cytology and mri scans provide some useful information, but most cases will require surgical excision as. We usually look like our parents because they are the source of our dna.
Salivary gland tumors information mount sinai new york. There are several pairs of salivary glands in different locations a major pair in front of the ears parotid glands. Diagnosis of diseases of the large salivary glands of the head by ultrasound, sialography and ctsialography. Longterm results are related to the grade of the cancer. Pathogenesis and histogenesis of salivary gland tumours prezi. Salivary gland tumors after childhood radiation treatment for benign conditions of the head and neck. Salivary cancers form in tissues of salivary glands in the floor of the mouth and throughout the oropharynx, the parotid glands, and the submandibular glands.
Their complexity is attributed to heterogeneity of the cells of. Ppt salivary gland imaging powerpoint presentation. Salivary gland tumors tehran university of medical sciences. In children and adolescents, salivary gland tumors make up 0. Salivary gland tumors are rare, and information on management of locoregional and metastatic disease is based on retrospective series and phase ii trials, most commonly in acc. Although we know a few things that can raise a persons risk of salivary gland cancer, its not clear exactly what causes most of these cancers cancer is caused by changes in the dna inside of cells. Use of wireless phones and the risk of salivary gland. Most salivary gland tumors are benign and occur in the parotid glands.
This is the most common salivary gland malignancy 2025 per cent of all malignant salivary gland neoplasms, occurs at mucosal sites more frequently than in major salivary glands, and accounts for 26 per cent of parotid tumours and approximately 15 per cent of submandibular tumours. Salivary gland tumors is the property of its rightful owner. Use of wireless phones and the risk of salivary gland tumours. Ppt salivary gland tumors powerpoint presentation free to download id. Salivary gland tumors definition of salivary gland. Seroustype acini of a parotid gland with dense secretory granules histologic section of a submaxillary gland. Salivary gland neoplasm an overview sciencedirect topics. Acinic cell carcinoma 3% of all salivary gland neoplasm 8090% in parotid 15% of all parotid tumors mean age is 4050 years 23 occur in female 3% shows bilateral involvement second most common salivary gland tumor in children well circumscribed tumor with fibrosis tissue macroscopically. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Salivary gland cancer, adult genetic and rare diseases. Oct 26, 2018 you have three pairs of major salivary glands parotid, sublingual and submandibular.
Salivary gland tumors msd manual professional edition. The sections show a stratified squamous epithelium with a thin layer of parakeratosis, minor salivary glands, and a wellcircumscribed cystic lesion. More than half of all salivary gland tumors are benign not cancerous and do not spread to other tissues. Description the tongue, cheeks, and palate the hard and soft areas at the roof of the mouth contain many glands that produce saliva. There are also hundreds of small minor salivary glands lining parts of the mouth, nose, and larynx that can be seen only with a microscope. Still in the us, carcinomas of the major salivary glands comprise 11% of oropharyngeal neoplasms. Salivary gland tumors sgts are rare neoplasms accounting for 0.
High grade transformation in salivary gland carcinomas, a. A painless salivary mass is the most common sign and is evaluated by fineneedle aspiration biopsy. Being exposed to certain types of radiation may increase the risk of salivary cancer. Ppt salivary gland tumors powerpoint presentation free.
The salivary glands make saliva and release it into the mouth. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Only a doctor familiar with a persons medical history, type of cancer, stage, characteristics of the cancer, treatments chosen and response to treatment can put all of this information together with survival statistics to arrive at a prognosis. The use of wireless phones was not associated with an overall increased risk of salivary gland tumours, odds ratio 0. What views are acquired in the salivary gland imaging. Cancer of the salivary glands commonly presents with one of several different histologies. What is the method of localization of the salivary glands. Mar 18, 2019 salivary gland neoplasms most commonly appear in the sixth decade of life. Prognosis and survival for salivary gland cancer canadian. Jun 01, 2015 salivary gland cancer is a rare disease in which cancerous cells form in the tissues of the salivary glands. Salivary gland tumours most often present as painless enlarging masses. They produce saliva, which moistens food to help with chewing and swallowing. Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain com.
Mid17th century anatomy of the parotid gland and the role of the main ducts. For salivary gland cancer, an endoscope is inserted into the mouth to look at the mouth, throat, and larynx. Generally, an ebook can be downloaded in five minutes or less. People with salivary gland cancer may have questions about their prognosis and survival. Salivary gland tumors ppt by dr gulzar a bhat authorstream. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours. Important structure that run through the parotid gland. An approach to the why is salivary gland pathology. Patients with malignant lesions typically present after age 60 years, whereas those with benign lesions usually present when older than 40 years. Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. However, if chemotherapy improves survival is unknown. The majority of salivary gland tumors occur in the parotid glands. Salivary gland tumors merck manuals professional edition.
An endoscope is a thin, tubelike instrument with a light and a lens for viewing. Differentiation of benign and malignant tumors is not the primary goal of ct and mri. Benign and malignant diseases of salivary glands 1. The incidence of salivary gland neoplasms as a whole is approximately 5. Pac was first proposed by evans and batsakis in 1984 as a distinct type of salivary gland carcinoma under the nomenclature of polymorphous low grade adenocarcinoma plga. An mri or ct scan can also show whether metastasis has occurred. Evolving concepts and new entities in the 2017 who. Salivary gland tumors symptoms and causes mayo clinic. The overall incidence of salivary gland tumors varies around the world from approximately 0.
Terminal branch of external carotid artery that divided into. Most are located in the parotid glands and most are benign. Mar 18, 2019 staging of malignant salivary gland tumors is important for predicting prognosis and for accurate comparison of treatment results. Neither was there an increased risk for the different phone types when calculated separately nor was there an increased risk for different latencies or when cumulative use was divided into. Most small salivary gland tumors begin in the palate roof of the mouth.
Each gland has its own tube duct leading from the gland to the mouth. Salivary gland tumors present as painless masses in the salivary glands either in front of the ear in the case of a parotid tumor, below the jaw in the case of a submandibular tumor, or in the mouth or throat in case of a sublingual or minor salivary gland tumor. Salivary gland tumors can begin in any of the salivary glands in your mouth, neck or throat. How much na 99mtco4 pertechnetate should be administered to the patient.
Salivary gland tumors tumors that arise from the salivary gland may arise from the salivary epithelium the parenchyma or the supportive stroma mesenchymal benign parenchymal tumors are known as adenomas malignant tumors are known as adenocarcinomas. Dna is the chemical in each of our cells that makes up our genes the instructions for how our cells function. Radiotherapy if a salivary gland tumour is cancerous, radiation therapy may be necessary fast neutron therapy has been used successfully to treat salivary gland tumors, 11 and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors. Salivary gland cancer is a rare disease in which cancerous cells form in the tissues of the salivary glands. Ppt salivary gland tumors powerpoint presentation free to. Chemotherapy is sometimes used as palliation for patients with salivary gland tumors not amenable to curative treatment. Be able to identify striated ducts of the salivary gland at the light and electron microscope level and correlate the structural features of the constituent cells to the. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Saliva has enzymes that help to digest food and antibodies that help protect against infections of the mouth and throat. If so, share your ppt presentation slides online with. The various types of salivary gland tumors are best distinguished by their histologic patterns. Greeks called paraauricular swellings described findings associated wi. The three main pairs of salivary glands are the parotid glands, the sublingual glands, and the submandibular glands. Cancer is caused by changes in the dna inside of cells.
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